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This alone is almost worth a permanent

Choose your own one at the beginning of the game and learn the gameplay as you go

Since the few anti-Poison tech cards are too narrow for most Commander metagames, opponents receiving their first Poison counters face an unappealing choice: either unapologetically gang up to immediately remove the proliferate deck from the game, or dont and then try to act surprised when that player inevitably wins the game a few triggers later

But honestly, I think its much more interesting to try to compile your own bespoke decks that can undo their ways

Awesome folks like Mike Balles have been sharing previews on Twitter