OSu-PEG4-VC-PAB-DMEA-Duocarmycin SA Size:1mg Product Name 2-{4-[2-(piperazin-1-yl)ethyl]piperazin-1-yl}ethan-1-amine Synonyms 2-{4-[2-(piperazin-1-yl)ethyl]piperazin-1-yl}ethanamine

Product Name 2-{4-[2-(piperazin-1-yl)ethyl]piperazin-1-yl}ethan-1-amine Synonyms 2-{4-[2-(piperazin-1-yl)ethyl]piperazin-1-yl}ethanamine CAS Number 135630-61-4 Related CAS Molecular Formula C12H27N5 Molecular Weight 241

Product Name DOTA-PEG4-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C26H48N8O11 Molecular Weight 648

88 Purity (HPLC) >= 95% Physical Appearance Red solid Optical Properties Abs/Em Maxima: 556/576 nm Solubility DMSO Shipping Conditions Shipped on gel packs Storage Conditions Store at -20°C and protected from light Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide fluoride Synonyms Thalidomide-4' fluoride CAS Number 835616-60-9 Related CAS Molecular Formula C13H9FN2O4 Molecular Weight 276

m-PEG8 is attached to the commonly used self-immolative para-aminobenzyl (PAB) moiety to further increase aqueous solubility

OSu-PEG4-VC-PAB-DMEA-Duocarmycin SA Size:1mg Product Name 2-{4-[2-(piperazin-1-yl)ethyl]piperazin-1-yl}ethan-1-amine Synonyms 2-{4-[2-(piperazin-1-yl)ethyl]piperazin-1-yl}ethanamineOSu PEG4 vc PAB DMEA Duocarmycin SA is a cleavable ADC druglinker conjugate that couples the potent antitumor antibiotic Duocarmycin SA to an OSu PEG4 vc PAB DMEA linker. The DNA? modifying agents such as duocarmycin are increasingly used in the development of antibody? drug conjugates (ADCs), where they serve as highly potent cytotoxic payloads. Designed for ADC research, this construct supports efficient antibody conjugation, PEG4? enhanced