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DBCO-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE Size:5mg 01 SMILES CNC(=O)COC1=CC2=C(C=CC(=C2)N(C)C2=NC(=NC=C2Cl)N2C[C@@H](C)C[C@@H](C)C2)N(C)C1=O Purity (HPLC)

SKU: 76075348815

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Description

01 SMILES CNC(=O)COC1=CC2=C(C=CC(=C2)N(C)C2=NC(=NC=C2Cl)N2C[C@@H](C)C[C@@H](C)C2)N(C)C1=O Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

Product Name Phthalimidinoglutarimide-C6-OH Synonyms Phthalimidinoglutarimide-4'-C6-OH CAS Number n/a Related CAS Molecular Formula C19H24N2O4 Molecular Weight 344

with sulfonic acid groups that enhance its solubility in water and reduce aggregation

Westermann

667 Purity (HPLC) >= 95% Solubility DMSO

DBCO-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE Size:5mg 01 SMILES CNC(=O)COC1=CC2=C(C=CC(=C2)N(C)C2=NC(=NC=C2Cl)N2C[C@@H](C)C[C@@H](C)C2)N(C)C1=O Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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