Use efficient removal I feel bad saying something so obvious, but in a metagame dominated by Decay and Lilly, as well as decks that don't want to interact at all, Infect has a huge edge
Of course, if you operate under the assumption that this is going to be a 7/7 every time, which might end up being the case, this card is actually pretty good
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I had great success with a Marowak EX deck, which was heavily chance-based (Marowak does massive damage or no damage, based entirely on two coin tosses), but can be set up super fast, allowing you to get in there and, with a bit of luck, wipe out a powerful EX card of your opponents before they can properly set up