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This is pretty easy to grow in most decks, especially if you've got lots of lizards around

For particularly unlucky bastards a plasma shot can destabilize their entire structural being, reducing them down to a pile of radioactive goop as depicted in the artwork and effect of this card

Have at least one instant-speed nuke or snipe

Mycosynth Golem Mycosynth Golems one of the more restrictive cards here since it only affects artifact creatures, but I can get behind a freeor almost freeCityscape Leveler or Phyrexian Triniform, especially considering how easily affinity powers this golem out